Infection of the vesicular gland is seldom reported. Vesicular adenitis is cultured but normals - not so much.
Garcia et al (2021 reported on recovery of Campylobacter fetus subsp venerealis from a naturally challenged bull. There were no lesions.
García JA, Gioffré AK, Acuña J, Méndez MA, Morsella C, Aller JF, Paolicchi FA. Isolation of Campylobacter fetus subsp. venerealis from seminal vesicle of a naturally challenged bull. Vet Res Commun. 2021; 45: 447-452.
Vesicular adenitis, often
with inflammation in ampullae, is a common lesion in
the bull. Vesicular
adenitis in bulls is detected on rectal palpation, and by the presence of
neutrophils or pus in semen. Young bulls, less than 2 years of age, are
frequently affected. They usually recover within 3 to 6 weeks.
The prevalence is about 1-5% of bulls with the lower numbers in range bulls. The young and the very old are particularly represented.
Bacteria are commonly isolated from cases and most of the bacteria are Trueperella pygenes. Corynebacterium pseudotuberculosis is occasionally isolated.
Little is known of the pathogenesis of vesicular adenitis. It is known that seminal vesicular fluid and seminal plasma inhibits the function of neutrophils both by reducing transmigration and inhibiting the effect of reactive oxygen species.
Carrol et al (1968) reported on 10 cases. All were young bulls. 8 had reduced fertility with leukocytes in the semen. 3 of 4 bulls with semen culture had Trueperella (Corynebacterium) pyogenes. Those clinically affected have the characteristic lesions, but subclinical infection occurs and unaffected bulls may be microscopic lesions. Most affected bulls had lesions in other organs. 3 of their 10 had epididymitis too.
Aloé S, Weber F, Behr B, Sauter-Louis C, Zerbe H. (2012) Modulatory Effects of Bovine Seminal Plasma on Uterine Inflammatory Processes. Reprod Dom Anim 2012; 47: 12-19
Carroll EJ, Ball L, Young S. Seminal vesiculitis in young beef bulls. J Am Vet Med Assoc. 1968; 152: 1749-1757
Martınez MF, Arteaga AA, Barth AD. (2008): Intraglandular injection of antibiotics for the treatment of vesicular adenitis in bulls. Animal Reproduction Science 2008; 104 201–211